Week 5 College Football Predictions

Week 4 is done and man has this season gone by fast! Welcome to Pypeline’s Week 5 college football predictions. I’ll predict every game, big or small.

As always, join us before kickoff on twitter. We’ll talk about the match-ups, answer any fantasy questions, and get you ready for an action-packed day of football. And check out my picks against the spread at the end, because who doesn’t love watching college football AND making money?

Zach Bolinger/Icon Sportswire/Getty Images

Top 25


  • (1) Clemson 48 North Carolina 14
  • (2) Alabama 52 Ole Miss 10
  • (5) Ohio State 49 Nebraska 27
  • (6) Oklahoma 52 Texas Tech 24
  • (7) Auburn 27 Mississippi State 20
  • (8) Wisconsin 31 Northwestern 7
  • (9) Florida 45 Towson 14
  • (10) Notre Dame 27 (18) Virginia 20
  • (12) Penn State 27 Maryland 20
  • (14) Iowa 38 Middle Tennessee 13
  • (15) California 20 Arizona State 13
  • (17) Washington 31 (21) USC 24
  • (19) Utah 45 Washington State 37
  • (20) Michigan 38 Rutgers 14
  • (22) UCF 52 UConn 7
  • (23) Texas A&M 38 Arkansas 10
  • Oklahoma State 34 (24) Kansas St 27
  • (25) Michigan State 31 Indiana 20

Top Unranked Games


  • Virginia Tech 27 Duke 24
  • Memphis 31 Navy 24
  • Toledo 27 BYU 24
  • TCU 31 Kansas 20
  • Temple 27 Georgia Tech 16
  • Baylor 31 Iowa State 28
  • Minnesota 31 Purdue 27
  • Wake Forest 42 Boston College 28
  • SMU 42 USF 28
  • Cincinnati 24 Marshall 21
  • Arkansas State 33 Troy 31
  • Louisiana 34 Georgia Southern 27
  • Oregon State 35 Stanford 34
  • South Carolina 27 Kentucky 24
  • Florida State 31 NC State 24
  • Arizona 49 UCLA 38
Melina Myers-USA TODAY Sports

FBS vs FCS


  • Pittsburgh 38 Delaware 7
  • Texas State 27 Nicholls 24
  • Syracuse 59 Holy Cross 7

Conference Games


  • Air Force 31 San Jose State 17
  • Buffalo 28 Miami OH 20
  • Western Michigan 31 CMU 24
  • Appalachian State 38 Coastal Carolina 24
  • Charlotte 34 Florida Atlantic 28
  • Louisiana Tech 30 Rice 17
  • ULM 44 South Alabama 33
  • UAB 31 WKU 23
  • Utah State 45 Colorado State 24
  • Wyoming 27 UNLV 17
  • Nevada 42 Hawaii 38
  • Southern Miss 45 UTEP 14
Andrew Dye / Winston-Salem Journal

Rest of the Week 4 Slate


  • North Texas 38 Houston 28
  • Fresno State 45 New Mexico State 20
  • Old Dominion 27 East Carolina 20
  • Vanderbilt 27 Northern Illinois 20
  • Akron 34 UMass 24
  • Liberty 45 New Mexico 31

Weekly Predictions Record


  • Straight Up: 245-39
  • Free ATS Picks: 20-15-1

Week 5 Free Picks ATS


  • Baylor +3 vs Iowa State
  • UVA +12.5 vs Notre Dame
  • Oregon State +4 vs Stanford
  • Toledo +2 vs BYU
  • Buffalo -1 vs Miami OH
  • SMU -7 vs USF
  • Utah -5.5 vs WSU
  • Vanderbilt -6.5 vs Northern Illinois